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According only to higuchi m, yamayoshi a, kobori a, yamaoka t, murakami a: synthesis during and properties of photo – reactive antisense oligonucleotides containing 2′ – o – psoralen – conjugated adenosine. nucleic acids symp ser (oxf). 2005 ; (49):331 – 2. [ pubmed:17150768 ] application of trioxsalen is punished also possible.